@Publications in Journals and Text Books


Genomics


Sequence variants at the myostatin gene locus influence the body composition of Thoroughbred horses. Tozaki T, Sato F, Hill E W, Miyake T, Endo Y, Kakoi H, Gawahara H, Hirota K, Nakano Y, Nambo Y, Kurosawa M. J. Vet. Med Aci. 73(12) 1617-1624, 2011.

Construction and validation of parentage testing for Thoroughbred horses by 53 single nucleotide polymorphisms. Hirota K, Kakoi H, Gawahara H, Hasegawa T, Tozaki T. J. Vet. Med. Sci. 72, 719-726, 2010.

A genome-wide association study for racing performances in Thoroughbreds clarifies a candidate region near the MSTN gene. Tozaki T, Miyake T, Kakoi H, Gawahara H, Sugita S, Hasegawa T, Ishida N, Hirota K, Nakano Y. Animal Genetics. 41 (Suppl. 2), 28-35, 2010.

A genome-wide scan for tying-up syndrome in Japanese Thoroughbreds. Tozaki T, Hirota K, Sugita S, Ishida N, Miyake T, Oki H, Hasegawa T. Animal Genetics. 41 (Supple. 2), 80-86, 2010.

Genome sequence, comparative analysis, and population genetics of the domestic horse. Wade CM, Giulotto E, Sigurdsson S, Zoli M, Gnerre S, Imsland F, Lear L, Adelson DL, Bailey E, Bellone RR, Blocker H, Distl O, Edgar RC, Garber M, Leeb T, Mauceli E, Macleod JN, Penedo MCT, Raison JM, Sharpe T, Vogel J, Andersson L, Antczak DF, Biagi T, Binns MM, Chowdhary BP, Coleman SJ, Della Valle G, Fryc S, Guerin G, Hasegawa T, Hill EW, Jorka J, Kiialainen A, Lindgren G, Liu J, Magnani E, Mickelson JR, Murray J, Nergadze SG, Onofrio R, Pedroni S, Piras MF, Raudsepp T, Rocchi M, Roed KH, Ryder OA, Searle S, Skow L, Swinburne JE, Syvanen AC, Tozaki T, Valberg SJ, Vaudin M, White JR, Zody MC, Broad institute genome sequencing platform, Broad institute whole genome assembly team, Lander ES, Lindblad-Toh K. Science. 326, 865-867, 2009.

Seven novel KIT mutations in horses with white coat colour phenotypes. Haase B, Brooks SA, Tozaki T, Burger D, Poncet PA, Rieder S, Hasegawa T, Penedo C, Leeb T. Animal Genetics. 40, 623-629, 2009.

SNP detection and radiation hybrid mapping in horses of nine candidate genes for temperament. Momozawa Y, Takeuchi Y, Tozaki T , Kikusui T, Hasegawa T, Raudsepp T, Chowdhary BP, Kusunose R, Mori Y. Animal Genetics. 38, 81-91, 2007.

Improved resolution of the comparative horse-human map: Investigating markers with in silico and linkage mapping approaches. Tozaki T, Swinburne J, Hirota K, Hasegawa T, Ishida N, Tobe T. GENE. 392, 181-186, 2007

Whole-genome linkage disequilibrium screening for complex traits in horses. Tozaki T, Hirota K, Hasegawa T, Ishida N, Tobe T, Mol Genet Genomics. 277, 663-672, 2007.

Estimation of heritability and genetic correlation for behavioural responses by Gibbs sampling in the thoroughbred racehorse. Oki H, Kusunose R, Nakaoka A, Nishiura H, Miyake T, Sasaki Y. J Anim Breed Genet. 124, 185-191, 2007.

Single linkage group per chromosome genetic linkage map for the horse, based on two three-generation, full-sibling, crossbred horse reference families, Swinburne JE, Boursnell M, Hill G, Pettitt L, Allen T, Chowbhary B, Hasegawa T, Kurosawa N, Leeb T, Mashima S, Mickelson JR, Raudsepp T, Binns TTM. Genomics. 87, 1-29, 2006.

Construction of a medium-density horse gene map. Perrocheau M, Boutreux V, Chadi S, Mata X, Decaunes P, Raudsepp T, Durkin K, Incarnato D, Lannuzzi L, Lear TL, Hirota K, Hasegawa T, Zhu B, P de Jong, Cribiu EP, Chowdhary BP. Animal Genetics. 37, 145-155, 2006.

Polymorphism identification, RH mapping, and association analysis with the anxiety trait of the equine serotonin transporter(SLC6A4) gene, Momozawa Y, Tozaki T, Kikusui TR, Hasegawa T, Raudasepp T. Chowdhary BP, Kusunose R, Mori Y. J Vet Med Sci. 68(6), 619-621, 2006.

Estimation of heritability for tying-up syndrome in the Thoroughbred racehorses by gibbs sampling, Oki H, Miyake T, Hasegawa T, Sasaki Y, Anim J. Breed Genet. 122, 289-293, 2005.

Association between equine temperament and polymorphisms in dopamine D4 receptor gene, Momozawa Y, Takeuchi Y, Kusunose R, Kikusui T, Mori Y. Mammalian Genome. 16, 538-544, 2005.

Prospects for whole genome linkage disequilibrium mapping in thoroughbreds, Tazaki T, Hirota K, Hasegawa T, Tomita M, Kurosawa M. Gene. 346, 127-132, 2005.

Sequences, detection of polymirphisms and radiation hybrid mapping of the equine catechol-o-methyltransferase genome. Momozawa Y, Takeuchi Y, Tozaki T, Kikusui T, Hasegawa T, Raudosepp T, Chowdhary BP, Kusunose R, Mori Y. Anim Genetics. 36, 190, 2005.

International equine gene mapping workshop report : a comprehensive linkage map constructed with data from new markers and by merging four mapping resources. Penedo MCT, Millon LV, Bernoco D, Baily E, Binns M, Cholewinski G, Ellis N, Flynn J, Gralak B, Guthrie A, Hasegawa T, Lingren G, Lyons LA, Roed KH, Swineburne JE, Tozaki T. Cytogenet Genome Res. 111, 5-15, 2005.

Nucleotide sequence of equine erythropoietin and characterization of region-specific antibodies. Sato H, Yamashita S, Kugo T, Hasegawa T, Mitsui I, Kijima-Suda I. Am J Vet Res. 65(1), 15-19, 2004.

Isolation, characterization and chromosome assignment of 341 newly isolated equine microsatellite markers. Tozaki T, Penedo MCT, Oliveira RP, Katz JP, Millon LV, Ward T, Pettigrew DC, Brault LS, Tomita M, Kurosawa M, Hasegawa T, Hirota K. Int Society Animal Genetics. 35, 487, 2004.

The second generation of the international equine gene mapping workshop half-sibling linkage map. Guerin G, Bailey E, Bernoco D, Anderson I, Antczak DF, Bell K, Biros I, Bj_rnstad G, Bowling AT, Brandon R, Caetano AR, Cholewinski G, Colling D, Eggleston M, Ellis N, Flynn J, Gralak B, Hasegawa T, Ketchum M, Lindgren G, Lyons LA, Millon LV, Mariat D, Murray J, Neau A, R_ed K, Sandberg K, Skow LC, Tammen I, Tozaki T, Van Dyk E, Weiss B, Young A, Ziegle J. Animal Genetics. 34, 161-168, 2003.

Microsatellite variation in Japanese and Asian horses and their phylogenetic relationship using a European horse outgroup, Tozaki T, Takezaki N, Hasegawa T, Ishida N, Kurosawa M, Tomita M, Saitou N, Mukoyama H. J Hered. 94(5),374-80, 2003.

The second generation of the international equine gene mapping workshop half-sibling linkage map. Gue'rin G, Bailey E, Bernoco D, Anderson I, Antczak DF, Bell K, Biros I, Bjo/rnstad G, Bowling AT, Brandon R, Caetano AR, Cholewinski G, Colling D, Eggleston M, Ellis N, Flynn J, Gralak B, Hasegawa T, Ketchum M, Lindgren G, Lyons LA, Millon LV, Mariat D, Murray J, Neau A, Ro/ed K, Sandberg K, Skow LC, Tammen I, Tozaki T, Van Dyk E, Weiss B, Young A, Ziegle J. Animal Genetics. 34, 161-168, 2003.

Molecular cloning, nucleotide sequence and presence of multiple functional polyadenylation signals in the 3'-untranslated region of equine dopamine beta-hydroxylase cDNA. Sato F, Hasegawa T, Katayama Y, Ishida N. DNA Sequence. 13 (5), 257-262, 2002.

Immunohistochemical localization of chromogranin A in the acinar cells of equine salivary glands contrasts with rodents glands. Sato F, Kanno T, Nagasawa S, Yanaihara N, Ishida N, Hasegawa T, Iwanaga T. Cells Tissues Organs. 172, 29-36, 2002.

Determination and variability of neucleotide sequences for D4 dopamine receptor genes (DRD 4) in genus Equus. Hasegawa T, Sato F, Ishida N. J Equine Sci. 13 (2), 57-62, 2002.

Molecular cloning of equine (Thoroughbred) myostatin cDNA and detection of myostatin precursor proteins in the serum. Hosoyama T, Kawada S, Oshiumi R, Yoneda S, Soeta C, Yamanouchi K, Hasegawa T, Ishida N, Mukoyama H, Ishii N, Tachi C. J Reprod & Dev. 48(4), 335-342, 2002.

Increased concentrations of protein gene product 9.5 in the synovial fluid from horses with osteoarthritis. Kitamura H, Okumura M, Sato F, Kimoto K, Kohma M, Hashimoto Y, Tagami M, Iwanaga T. J Vet Res. 49(2), 115-123, 2001.

FISH assignment of two equine BAC clones containing SRY and ZFY. Hirota K, Piumi F, Sato F, Ishida N, Guerin G, Miura N, Hasegawa T. Anim Genetics. 32, 326, 2001.

X chromosome detection in an XO mare using a human X paint probe, and PCR detection of SRY and amelogenin genes in 3 XY mares. Makinen A, Suojala L, Nishi T, Katila T, Tozaki T, Miyake Y-I, Hasegawa T. Equine vet J. 33(5), 527-530, 2001.

Molecular cloning of horse Hsp90 cDNA and its comparative analysis with other vertebrate Hsp90 sequences. Pepin K, Momose F, Ishida N, Nagata K. J Vet Med Sci. 63(2), 115-124, 2001.

Immunohistochemical demonstration of chromogranin A in endocrine organs of the rat and horse by use of region-specific antibodies. Hashimoto Y, Ohki H, Sato F, Yanaihara N, Iwanaga T. J Vet Res. 49(1), 13-17, 2001.

Expression of steroidogenic enzyme genes in the equine feto-placental unit. Hasegawa T. Sato F, Nambo Y, Ishida N. J Equine Sci. 12(1), 25-32, 2001.

Population study and validation of paternity testing for Thoroughbred horses by 15 microsatellite loci. Tozaki T, Kakoi H, Mashima S, Hirota K, Hasegawa T, Ishida N, Miura N, Miura NC, Tomita M. J Vet Med Sci. 63(11), 1191-1197, 2001.

Equine follicle-stimulating hormone : Molecular cloning of _ subunit and biological role of the asparagine-linked oligosaccharide at asparagine56 of _ subunit. Saneyoshi T, Min K-S, Ma XJ, Nambo Y, Hiyama T, Tanaka S, Shiota K. Biol Reprod. 65, 1686-1690, 2001.

Expression of equine chromogranin A cDNA sequence and distribution of mRNA in endocrine and exocrine tissues. Sato F, Ishida N, Hasegawa T, Katayama Y, Kanno T, Yanaihara N, Ohki H, Iwanaga T, Mukoyama H. Adv Exp Med Biol. 482, 137-142, 2000.

The isolation and characterization of 18 equine microsatellite loci, TKY272-TKY289. Tozaki T, Kakoi H, Mashima S, Hirota K, Hasegawa T, Ishida N, Miura N, Tomita M. Anim Genetics. 31, 149-150, 2000.

Molecular cloning of equine chromogranin A and its expression in endocrine and exocrine tissues. Sato F, Hasegawa T, Katayama Y, Iwanaga T, Yanaihara N, Kanno T, Ishida N. J Vet Med Sci. 62(9), 953-959, 2000.

Sex determination by simultaneous amplification of equine SRY and amelogenin genes. Hasegawa T, Sato F, Ishida N, Fukushima Y, Mukoyama H. J Vet Med Sci. 62(10), 1109-1110, 2000.

Identification of skeletal muscle satellite cells by transfecting EGFP driven by skeletal BF-Actin promoter. Yamanouchi K, Soeta C, Suzuki S, Hasegawa T, Naito K, Tojo H. J Vet Med Sci. 62(11), 1213-1216, 2000.

Genomic organization in the amino acid coding sequence of equine CYP gene. Hasegawa T, Sato F, Ishida N. J Equine Sci. 11(4), 99-105, 2000.